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Search Results for " melk inhibitor "

11

Compounds

Cat No. Product Name Synonyms Targets
T11996 MELK-8a hydrochloride MELK
MELK-8a hydrochloride is a potent inhibitor of maternal embryonic leucine zipper kinase (MELK, IC50 = 2 nM). 
T11997 MELK-IN-1 Nintedanib Impurity L,MELK inhibitor 17 MELK
MELK-IN-1 (MELK inhibitor 17) is a potent inhibitor of maternal embryonic leucine zipper kinase (MELK),(IC50:3nm;Ki:0.39 nM).
T1759 OTSSP167 MELK inhibitor,OTS167 MELK
OTSSP167 (OTS167) is an orally available inhibitor of maternal embryonic leucine zipper kinase (MELK) with potential antineoplastic activity.
T21559 OTSSP167 hydrochloride MELK
OTSSP167 hydrochloride is a highly potent inhibitor of MELK(IC50 : 0.41 nM).
T4327 Prexasertib dihydrochloride LY2606368 (dihydrochloride),Prexasertib HCl,LY2606368 Apoptosis , Chk , S6 Kinase
Prexasertib dihydrochloride (LY2606368) is an ATP-competitive CHK1 inhibitor (Ki: 0.9 nmol/L). in the cell-free assay, its IC50 values are 8 nM and 9 nM for CHK2 and RSK, respectively.
T4310 Prexasertib LY2606368 Apoptosis , Chk
Prexasertib (LY2606368) is an inhibitor of checkpoint kinase 1 (chk1) with potential antineoplastic activity.
T24152 HTH-01-091 HTH-01091,HTH01-091,HTH 01-091,HTH 01091 Serine/threonin kinase , Pim , MELK , DYRK , CDK , RIP kinase
HTH-01-091 is a potent and selective maternal embryonic leucine zipper kinase (MELK) inhibitor (IC50: 10.5 nM).HTH-01-091 inhibits PIM1/2/3, RIPK2, DYRK3, smMLCK and CLK2. HTH-01-091 can be used to study breast cancer.
T62417 MELK-8a
MELK-8a (NVS-MELK8a) is a potent and selective inhibitor of maternal embryonic leucine elongation kinase (MELK) (IC50: 2 nM). 0.42 μM). Among them, MELK plays an important role in regulating mitosis in cancer cells.
T71197 JW-7-25-1
JW-7-25-1 is a potent multi-target inhibitor, acting on MELK, PIK3CA, mTOR, GSK3A and CDK7.
T11725 JNJ-47117096 hydrochloride MELK-T1 hydrochloride Others
JNJ-47117096 hydrochloride is potent and selective MELK inhibitor, with an IC50 of 23 nM, also effectively inhibits Flt3, with an IC50 of 18 nM.
T73867 HTH-01-091 TFA
HTH-01-091 TFA, a potent and selective inhibitor of maternal embryonic leucine zipper kinase (MELK), exhibits an IC50 of 10.5 nM. Besides its primary target, it also inhibits PIM1/2/3, RIPK2, DYRK3, smMLCK, and CLK2, pos...
TargetMol